From the relatively compact Altstadt to the large Marktplatz, Mainz offers a wide selection of cultural attractions appealing to all ages and interests. Some of the most popular options include the Cathedral and Diocesan Museum, the Landesmuseum Mainz and Gutenberg Museum providing deep insight in the history of the city.

To accommodate its visitors Mainz offers a range of lodges, from international chain hotels to small bed and breakfast inns. Some of the most popular hotels in Mainz include Hilton Mainz, Hyatt Regency Mainz, Mainz City Hilton, Hotel Mainzer Hof and Hotel Ibis just to name a few. Ranked with the most imaginatively designed hotels in Mainz, Hilton Mainz is situated in the city center, close to all major sights and attractions. The twin sections of the hotel are connected by glass-sided covered walkway, while the labyrinthine interior features sun-flooded atriums with live plants. Guest rooms are spacious and regarded as the most artfully decorated in Mainz. Hotel facilities include two restaurants, two bars, sauna, health club, salon, solarium, babysitting, limited room service, dry cleaning, laundry service, casino, non-smoking rooms and rooms for those with limited mobility.

A choice of many business and leisure travelers, Hyatt Regency Mainz is recognized as the best hotel in Mainz, designed in a modern architectural style. The glittering aura prevails in guest accommodations, restaurants and public rooms. Room furnishings are sophisticated, with modern art decorations. Spacious guest rooms feature deluxe toiletries and shower/tub combinations. The public facilities are ranked with the best in this part of the country, with the Bellpepper Restaurant and a wine bar featuring a grand terrace along the Rhine River. Guests can take advantage of the following hotel facilities: two restaurants, bar, beer garden, lounge, fitness center, babysitting, dry cleaning, laundry service and non-smoking rooms.

Located in the historic zone of Mainz, Mainz City Hilton is the ideal option for travelers on Mainz vacations and short city breaks. The lively atmosphere and even more personable staff make the hotel one of the most popular in the city. Guest rooms are spacious and tasteful, each featuring a deluxe bathroom with deep tubs and shower stalls. They are priced in accordance with the location and view. Hotel facilities include restaurant, two bars, babysitting, 24-hour room service, laundry service, dry cleaning, cabaret theater and rooms for people with limited mobility.

Another worthy choice, Hotel Mainzer Hof is a modern lodge directly on the Rhine River, at the point where many boats dock. The medium sized guest rooms are beautifully furnished and well maintained, and are equipped with bathrooms with tub/shower combinations. The list of hotel facilities is not as extensive as in other Mainz hotels and includes bar, lounge, solarium, sauna, laundry service, dry cleaning, limited room service and non-smoking rooms.

For fined dining visitors to Mainz are welcome to Geberts Weinstuben housed in one of the oldest buildings in the city, and Haus des Deutsches Weines focusing on a combination of German food and wines.