Skin grafting procedure is a surgery of placing skin or skin substitute over a non-healing wound or burn. As a matter of fact, there are three graft types used in a skin grafting procedure nowadays: allograft, autograft and xenograft. An autograft is known as one of the graft types which uses skin from other areas of the patient`s body. An allograft uses skin obtained from another person (donor). And xenograft uses the animal skin (often that of a pig). Be aware that xenografts and allografts are able to provide only temporary covering of the body. As a rule, these graft types are rejected by the patient`s immune system for being nonhuman. So, it has become evident that the basic issue regarding skin grafting procedure is skin grafting donor selection. The best skin for being used in skin grafting procedure is, no doubt, the patient`s own skin, which can be taken from other (undamaged) human body sites. They are often taken from the areas which are generally not visible (for example, an inner thigh or a buttock). It is important to take into consideration the donor skin visibility and color match. As a rule, taking the patient`s own skin can be possible in case there`s enough undamaged skin available and if the person`s health condition is good enough to undergo skin grafting procedure. As it has already been mentioned sometimes skin grafting procedure requires other people`s skin. Such skin is generally called a heterologous graft. Speaking about skin grafting procedure, it is relevant to say some words about full-thickness and split-thickness skin grafting. Thus, a full-thickness skin graft, including the entire skin thickness, may be necessary for rather extensive tissue loss. As a rule, this happens with the lower leg open fractures. Of course, this procedure is considered to be a more complicated one. It means transplantation of the skin flap with all the underlying muscles and blood vessels onto the necessary area. Among other common donor sites are skin flaps from the abdominal wall or the back. It is interesting to admit that in some cases the skin flat is taken from one site (for instance, the leg) while underlying muscles are taken from another site (for instance, the back). In some cases the patient requires the removal of the thin skin stripes and slices from the donor. Then a special surgical instrument – the so-called dermatome - is used. Such a procedure is called split-thickness skin grafting. The graft is being carefully spread on the bare area and covers it. The procedure is performed either by few small stitches or by careful pressure from the well-padded dressing. By the way, within the 36 hours after the procedure new blood vessels begin to grow into the transplanted skin. I can`t help mentioning that most skin grafting procedures are successful, but in some cases they may require repeat grafting. That`s why proper monitoring of skin graft is a must. If everything has been done correctly the recovery period doesn`t take long and almost no complications are seen.