Donor of eggs can be women who participate in the program of artificial fertilization or relatives of the recipient. Take advantage of the program fertilization donor's eggs can women having serious forms of infertility. To such pathologies concern full or partial absence of ovaries, hereditary genetic defects, infringement of functioning endocrine system, pathologies of reproductive system of not clear genesis.
The woman who agrees to become an egg donor should pass obligatory genetic consultation with a gynecologist. At absence of hereditary defects and diseases, the attending physician appoints to the donor the special circuit reception of hormonal preparations. The special program of hormonal therapy is appointed to the recipient, too. Hormonal preparations most frequently are entered with the help of injections. Injections can be carried out under domestic conditions. Therefore, the donor and the recipient receive special recommendations and pass injection training.
The purpose of the donor's hormonal therapy is for initiating egg prodecution. Significant dozes of hormones provoke occurrence of super-ovulation in the donor. At super-ovulation in ovary develop 3- 8 follicles. In each follicle there is one fetus egg. Thus, the probability of effective fertilization considerably grows. Egg prodecution of the donor should be synchronized with menstrual cycle of the recipient. Correct cycle coordination of egg prodecution of the donor and menstrual cycle of the recipient are provided with daily monitoring of ultrasonic. The level of hormones is supervised with the help of regular tests of blood at the recipient and the donor.
Egg prodecution has to last about 28 days. However, with the help of additional hormonal preparations this period can be reduced. At the end of egg production donor receives last doze of hormones and procedure of puncture is carried out. During the procedure of puncture the liquid and an egg is taken from follicles. The egg is exposed to fertilization of spermatozoon of recipient's husband or donor's spermatozoon. Further, development of an oosperm passes in vitro. In 7-10 days the embryo which is in stage of blastocysta, is transferred to the uterus of the recipient. Implantation of an embryo is accompanied by additional hormonal therapy. Supporting dozes of hormones are carried out until the 15th to 17th week of pregnancy.
The process of donor-egg reception is painful enough besides it is connected to the intake of big dozes of hormones. Thereof, donor egg ?production? is very lucrative and practiced in many countries of the word. Voluntary gratuitous donor service, however, is desirable. In most cases women who participate in the program of artificial fertilization, gratuitously transfer superfluous eggs for storage and for further fertilization. Donor's eggs are stored in special capacities with liquid nitrogen. The similar way of storage refers to as cryogenic preservation and is one of the most effective ways of preservation of viability eggs.