Your problem: You're single, Fresno is your hometown, and you want to get back into the dating scene. This is not a big a problem as you would have first thought.
The first thing is to check your threads and your ride. Find a friend whose fashion-sense you trust and go shopping with that person. Make sure that your style matches that of the present decade, and that you don't have too many bright or boring colors; you want to stand out from the crowd, not blind it or blend into the background. Neons may be great for raves, but you want to actually meet someone, something that doesn't really happen at there. Just remember: You need some color or you will remain single, Fresno is no exception.
Your ride is also a consideration. General rule: Just make sure that you have one. Every single Fresno male should have a way to get from Point A to Point B that doesn't involve the Three B's: bike, bus or best friend. The better the ride the better, but just make sure that the vehicle is presentable, and can carry two people without a potential date getting bugs in her teeth, and you're good to go. It's okay to carpool with your friends, as it saves on gas money (allowing you to but more drinks), defines the designated driver (make sure that he gets all the appetizers and juice that he wants), and gives you a support system as you look for Fresno girls, but you are limited to where the group goes and their schedule.
Also make that you have scouted the bar. Sometimes it can be fun to go to a random bar, but it's not conducive to finding single Fresno women. Each bar has its own rules and traditions, and it helps knowing what they are; for example, it doesn't help if you can't carry a tune and it's a karaoke bar. It also helps knowing what the ratio of men to women are; after all, you're not the only one going there looking for sex; Fresno can be a unforgiving mistress. It helps knowing the layout as well, so that you know where to dance, where to drink, and where to have fun. Scouting is half of the fun.
When you finally get there, be advised that you are a single Fresno male and that there are few single women looking for you. Remember three things, and you should do okay: First, stand out, but not obviously so. Read: Win contests, make jokes, and wear something bright, but don't be a sore loser, make fun of others, or wear neon. Second, stick up for your friends and the underdog; one makes sure that you have a ride, the other impresses those you want to impress. Third, always have story on hand that involves you getting hurt or humiliated, an opponent losing nonetheless, and you coming out on top; Fresno girls like that kind of thing for some reason.
And if the bar scene doesn't work out for you, keep in mind that internet dating is becoming more accepted every day. All it takes is the ability to be honest (lies will be caught and dealt with harshly), and the ability to talk fast and think faster. It's really not that hard to find a date online; just know what you are looking for, and present yourself as someone worth knowing, and you should do okay.